Etoposide相关论文
A significant proportion of non-small cell lung cancer(NSCLC)patients experience accumu-lating chemotherapy-related adve......
Enhanced intestinal absorption of etoposide from Self-microemulsifying drug delivery system in rats:
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Phase I study of etoposide and cisplatin chemotherapy dose escalation with concurrent radiotherapy f
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目的:探讨M-FISH技术在检测复杂核型中的价值。方法:联合应用常规细胞遗传学技术和M-FISH检测2例伴有复杂核型异常的急性髓细胞白......
1病例资料患者女,26岁。主诉“停经6个月,肝功异常13d伴厌油,乏力,胃胀,食欲不振,尿黄”门诊以“孕26周,妊娠急性脂肪肝?”于2009-......
目的利用抑制乳腺癌MDA-MB-231细胞中SK-1基因表达,结合依托泊苷对细胞增殖的影响,研究乳腺癌的治疗新方法。方法将依托泊苷分别处理......
第七届世界滋养细胞疾病会议于1994年11月6日至9日在香港举行。来自21个国家和地区的百余名代表出席了本次大会。兹将大会上交流......
本文报道3例患者使用依托泊甙(etoposide)治疗后产生急性呼吸暂停,且无喉痉挛及其它过敏反应特征。例1:男62岁,患有小细胞肺癌,预先给予......
郑州大学第一附属医院血液科对17例难治、复发急性白血病应用拓扑替康(topotecan,TPT)+依托泊甙(etoposide,VP16)+米托蒽醌(mitoxa......
Objective To evaluate the efficacy and safety of etoposide, methotrexate, actinomycin D, vincristine and cyclophosphami......
他莫昔芬是一种非甾类抗雌激素药 ,已广泛用于乳腺癌的治疗。据报道 ,高剂量他莫昔芬也被首次用于治疗黑素瘤 ,还试验用于治疗急性......
我们应用米托蒽醌 (MIT)、足叶乙甙 (VP1 6 )、阿糖胞苷 (Ara- C) ,简称MEA方案治疗急性髓系白血病 (AML )4 4例 ,取得较好的疗效......
The antitumor mechanism of etoposide (VP-16) is investigated using pulse radiolysis technology. The oxidizing mechanism ......
Construction of the Skeleton of Phthalascidin, Mechanism of the Formation of the Key Tricyclic Lacta
The mechanism of the formation of a key tricyclic lactam intermediate 3 was studied. It was found that the E-form compo......
背景与目的:体外及体内的临床研究显示,奥沙利铂(L-OHP)对多种肿瘤有显著抑制作用并与绝大多数抗癌药物具有相加或协同细胞毒作用......
近年来 ,血管内皮生长因子(VEGF)与血液恶性肿瘤关系日益受到重视 ,研究表明血液恶性肿瘤细胞高水平表达 VEGF,并不同程度表达 VEG......
对肿瘤发生发展的分子机制研究的最新进展表明 ,细胞凋亡障碍在肿瘤发病学上有重要的意义。在细胞凋亡的过程中Caspase家族起着关......
AIM:rAAV mediated endostatin gene therapy has beenexamined as a new method for treating cancer.However,a sustained and ......
目的 :分析同步放化疗(CRT)在NSCLC外科治疗的地位。方法 :回顾性总结 1987~1996年外科手术的 3 0例累及胸顶部的NSCLC ,单纯手术组......
目的 探索ELFP方案治疗转移复发的晚期鼻咽癌、食管癌、胃癌的临床疗效和毒性。方法 选择病理证实的 6 4例晚期鼻咽癌、食管癌、......
Cytotoxicity, apoptosis induction, and mitotic arrest by a novel podophyllotoxin glucoside, 4DPG, in
Aim: To define the in vitro cytotoxic activities of 4-demethyl-picropodophyllotoxin 7’-O-β-D-glucopyranoside (4DPG), ......
Multi-drug resistance is one of the leading causes for fai- lure to treat patients with cancer. This study is to explore......
The Experiment Research of Subconjunctival Injections with Etoposide for the Treatment of Retinoblas
Purpose: To evaluate the efficacy of subconjunctival injections of Etoposide for retinoblastoma(RB) mice.Method: Twenty-......
目的 评价口服依托泊苷治疗转移性乳腺癌的疗效和不良反应.方法 回顾性分析88例接受口服依托泊苷治疗的转移性乳腺癌患者资料.口服......
目的 探讨盐酸伊利替康联合顺铂治疗非小细胞肺癌(NSCLC)的临床疗效及不良反应.方法 非小细胞肺癌患者120例,随机分为观察组和对照......
目的观察洛铂联合依托泊苷治疗初治食管小细胞癌的疗效。方法16例初治食管小细胞癌患者全部使用洛铂与依托泊苷联合化疗方案治疗。......
Objective:Microtubule damaging agents such as nocodazole have been used in the clinical cancer chemotherapy. However, th......
目的 探讨应用小剂量米托蒽醌的MEA方案与常规剂量米托蒽醌MEA方案治疗老年急性髓系白血病的疗效. 方法 将42例老年AML患者分为两......
肺癌是世界上男女两性的一个主要死因。最近Bugger等报道对初期小细胞肺癌病人进行大剂量化疗和周围血干细胞移植取得了令人鼓舞......
我院1993年1月至1997年6月,应用HEAP[高三尖杉酯碱,足叶乙甙(etoposide,Vp-16),阿糖胞苷,泼尼松]方案治疗急性成人非淋巴细胞白血......
作者曾证明坎地沙坦(candesartan)血管紧张素Ⅱ受体阻断剂可于体外及体内抑制前列腺癌细胞的增长并发现前列腺癌细胞有血管紧张素......
Small cell carcinoma of the cervix(SCCC)belongs to the neuroendocrine carcinomas,and it is a rare gynecological tumor of......
Improved survival for hepatocellular carcinoma with portal vein tumor thrombosis treated by intra-ar
AIM: To investigate the poor prognosis of HCC with PVTT,we evaluated the efficacy by a new combination chemotherapy for ......
受试者为18例(男10例,女8例)21岁以下(平均11.4岁)的儿科实体瘤患者,除1例患有稳定性慢性肾功能衰竭而接受腹膜透析外,其他肝、肾......
Objective:The aim of our study was to evaluate the response and tolerability to treatment when using gemcitabine-cisplat......
程序性细胞死亡因子5(programmed celldeath5,PDCD5)在多种肿瘤细胞中表达明显降低。携带pdcd5基因的靶向增殖型腺病毒SG611-pdcd5......
Background and Objective:Chemotherapy is the main treatment for colon cancer,while multidrugresistance is the main reaso......
Time-resolved laser flash photolysis and pulse radiolysis have been used to study the chemical activity of podophyllotox......
本文报道用具电化学检测的HPLC 系统,可同时测定血清中的鬼臼类抗肿瘤药依托泊甙(Etoposide;VP16-213)和替尼泊甙(Teniposide;VM-......
Pedersen—Bjergaard等(1991年)报告,用含有足叶乙甙(etoposide)方案治疗胚胎细胞肿瘤可以增高骨髓发育不良和白血病的危险。本文......
植物抗肿瘤活性成分鬼臼毒素化学改造后的代表药物依托泊甙(etoposide)等自70年代进入临床后,不论其疗效和毒副反应均有不足之处......
为寻找高效低毒、结构简单的鬼臼毒素类新药,以4-溴-4′-去甲基-4-脱氧表鬼臼毒素和过量醇合成了13个新的4′-去甲基表鬼臼毒素-4-......